In the dark at 3am unable to sleep I reached into my bedside table drawer and took out what I thought was a sleeping tablet. As I used them so very rarely, they would work. I took the tablet and remained awake. What? Why? Well of course it wasn’t a sleeping tablet but I didn’t know that until the morning. So I had taken a placebo. No effect. So no, placebos don’t work for me. But also, if you know you have been given a placebo, why would it have any effect?